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REBEL mass spec device used to reduce toxic metabolite accumulation while increasing cell viability and titer by up to 40%

BOSTON–(BUSINESS WIRE)–908 Devices (Nasdaq: MASS), a pioneer of purpose-built handheld and desktop devices for chemical and biomolecular analysis, announced that its collaboration with CPI is demonstrating the value of at-line cell culture media analysis to inform feeding strategies for improved cell growth in bioprocessing applications. Using data from 908 Devices’ REBEL™ desktop device, CPI process engineers optimized nutrients of a monoclonal antibody-expressing cell line to increase titer and control toxic metabolites.

CPI process engineers used the REBEL device to monitor amino acid depletion across a panel of eight commercial cell culture media at high and low glucose concentrations in a 14-day fed-batch process in Ambr® 15 micro-bioreactors. Time course data from the REBEL provided unique insights into the cell metabolism, in addition to typical cell culture parameters. In a second run using the Ambr 15 system, these real-time data sets enabled refinement of media feeding strategies to correct amino acid depletion, improve cell viability and reduce toxic metabolite accumulation. Results of the tailored feeding approach, which used a low feed concentration and amino acid supplementation, enabled up to a 40% increase in titer while maintaining low levels of toxic metabolites.

The wealth of data provided by the REBEL along with multivariate modeling and statistical analysis enables users to make such informed decisions about their process as well as develop predictive models for feed control, leading to improved efficiency and robust product quality.

The REBEL analyzer integrates with the well-known and broadly used Umetrics® data software suite from Sartorius. Data from the REBEL can be seamlessly imported into MODDE® for design of experiments (DoE) and SIMCA® for rapid data visualization and multivariate trend tracking. CPI used SIMCA and MODDE to perform multivariate analysis of the REBEL data to expedite the identification of optimal feeding conditions.

CPI is an independent UK-based innovation organization that works with companies to develop, prove, scale up, and commercialize new products and processes. To learn more, view the webinar: Harness the Power of At-line Spent Media Analysis Using the REBEL to Optimize a CHO mAb Fed-Batch Process.

About the REBEL analyzer

REBEL is a first-of-its-kind fresh and spent media analyzer that enables biopharma researchers to accelerate process development cycles and maximize bioreactor utilization by running media analysis at-line. Key benefits include:

  • Efficiency – minimal sample preparation and tiny volume requirements
  • Real-time data tracking – quantitate over 30 key media nutrients in <10 minutes
  • Small and simple – versatile design valued by users across many applications

For more information, visit www.908devices.com.

Ambr, Umetrics, MODDE and SIMCA are registered trademarks of Sartorius AG. REBEL is a trademark of 908 Devices Inc.

About 908 Devices

908 Devices Inc. (Nasdaq: MASS) is democratizing laboratory mass spectrometry with its simple handheld and desktop devices, addressing critical-to-life applications. The Company’s devices are used at the point-of-need to interrogate unknown and invisible materials and provide quick, actionable answers to directly address some of the most critical problems in life sciences research, bioprocessing, pharma / biopharma, forensics and adjacent markets. The Company is headquartered in the heart of Boston, where it designs and manufactures innovative products that bring together the power of mass spectrometry, microfluidic separations, software automation and machine learning.

Forward Looking Statements

This press release includes “forward looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. All statements other than statements of historical facts are forward-looking statements, including, without limitation, statements regarding the expected uses and capabilities of the Company’s products. Words such as “may,” “will,” “expect,” “plan,” “anticipate,” “estimate,” “intend” and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) are intended to identify forward-looking statements. These forward-looking statements are based on management’s current expectations and involve known and unknown risks, uncertainties and assumptions which may cause actual results to differ materially from any results expressed or implied by any forward-looking statement, including the risks outlined under “Risk Factors” and elsewhere in the Company’s filings with the Securities and Exchange Commission which are available on the SEC’s website at www.sec.gov. Additional information will be made available in the Company’s annual and quarterly reports and other filings that it makes from time to time with the SEC. Although the Company believes that the expectations reflected in its forward-looking statements are reasonable, it cannot guarantee future results. The Company has no obligation, and does not undertake any obligation, to update or revise any forward-looking statement made in this press release to reflect changes since the date of this press release, except as may be required by law.

Contacts

Media
Barbara Russo
brusso@908devices.com

Investor
Carrie Mendivil
IR@908devices.com

The post 908 Devices and CPI Improve mAbs Cell Culture Outcomes Using At-line Media Analysis appeared first on Web Hosting | Cloud Computing | Datacenter | Domain News.

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Black Hawk supports 800G at unparalleled low power SAN JOSE, Calif.–(BUSINESS WIRE)–Credo, a global innovation leader in high-performance, low-power serial connectivity solutions, today announced it is expanding its product offering with Black Hawk (CRT55321) that leverages the company’s unique PAM4 DSP architecture to deliver industry-leading low power and reach. The PAM4 retimer and gearbox provide guaranteed, end-to-end signal integrity in backplane, front panel and copper applications. The CRT55321 expands the bandwidth capacity of next-generation network infrastructure at Hyperscale data centers, enterprise networks, and service providers while consuming less than 50% power of existing solutions. The CRT55321 is a 32-lane device that supports 16 lanes on the host side and 16 lanes on the line side. The extended reach performance provides robust signal integrity for PAM4 across the most difficult channels, including legacy backplanes. The device can be used in front…
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DENVER–(BUSINESS WIRE)–CoreSite Realty Corporation (NYSE:COR), a premier provider of secure, reliable, high-performance data center, cloud and interconnection solutions in major U.S. metropolitan areas, today announced it will host its third quarter 2020 earnings conference call on Thursday, October 29, 2020, at 12:00 p.m. Eastern Time, and will issue its financial results prior to market open on Thursday, October 29, 2020. The call will be accessible by dialing 1-877-407-3982 (domestic) or 1-201-493-6780 (international). A replay will be available until November 5, 2020, and can be accessed after the call by dialing 1-844-512-2921 (domestic) or 1-412-317-6671 (international). The passcode for the replay is 13710893. The earnings conference call also will be offered as a simultaneous webcast, accessible by visiting CoreSite.com and clicking on the “Investors” link. An on-line replay will be available for a limited time immediately following the call. About CoreSite…
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NEW YORK – TELEHOUSE America, a KDDI Group company and the global leader for data centers, international internet exchanges and managed IT services, today announced implementation of best-in-class layer physical security for their New York data centers with partner support. “We wanted a unified and modern security solution that could accommodate the latest technologies to ensure the highest security, internal team efficiency and auditing/reporting capabilities that protect our client assets,” explained, Telehouse Senior Director of the Corporate Division Milad Abdelmessih.

Telehouse America has been known for their security measures including monitored video surveillance and access control systems 24/7 at each site to ensure customer data remains fully secured and protected. The new system takes the facilities from a legacy system nearing end of life to a best-in-class layered security system that encompasses the Staten Island and Manhattan locations.


The security teams monitor a total of 400 cameras and 400 doors using both the Omnicast™ video surveillance system and the Synergis™ access control system of Security Center. This strengthens security through complete monitoring of all locations including every data center suite, corridors, elevators, and common areas. Essentially every door, access point into the building and the data center is monitored and controlled by the access control system.

With this update, Telehouse now has the ability to monitor the sites via a map-based interface that enables them to quickly find doors and nearby cameras. The platform’s open architecture includes a MAGOS radar perimeter detection system to spot potential threats at the property line, which is essentially a virtual fence around the site.

An advanced intercom system featuring a built-in Sipelia intercom module that enable two-way calling between Security Center operators and intercom devices at doors and shipping docks. This includes live video feed integration for visual identification of visitors and cardholders before granting or denying access.

A completely modernized visitor management process includes the installation of BioConnect fingerprint and facial recognition and Deister key management technologies. Genetec ClearID™ physical identity and access management modules automate visitor requests while keeping detailed audit trails of each visit.

The unified entry, access, and exit system with fully integrated surveillance enables Security Center operators to monitor visitor movements and quickly pull reports to conduct investigations if needed.

With as many as 50 rigorous audits per year, the new system transforms and simplifies the process through integrated reporting.

As a world-class data center provider, Telehouse America prides itself on ensuring best-in-class facilities, technologies, and security. According to Abdelmessih, this latest upgrade with the help of world-class system partners ensures the continuation of that legacy for Telehouse customers and staff:

“Since implementing the Security Center unified platform, securing our site and managing our visitors has become much easier. Having that unified security view ensures our staff can see what’s happening and respond without delay. Even from an operational standpoint, we’re delivering more value and assurance to our customers with detailed auditing and reporting. As we continue to evolve our security operations, I think Genetec will be a very long-term partner for us,” concluded Abdelmessih.

Learn more about this project via the upcoming Telehouse Case Study accessible at: https://www.telehouse.com/category/case-studies.

About Telehouse America
A stable and trusted pioneer of carrier-neutral data center services, TELEHOUSE offers secure, power-protected environments for clients to house and operate their telecommunications and network resources. One of the many benefits of using TELEHOUSE’s colocation service is its global availability of 47 TELEHOUSE-branded data centers in 23 cities throughout Asia, Africa, North America and EMEA. It enables customers to enjoy continuous, cost-effective IT connectivity around the world.

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United Kingdom, London – NTT Ltd.’s Global Data Centers division is expanding its worldwide co-location data center platform with new facilities across key markets. NTT Ltd., one of the world’s largest data center providers, operates a platform with over 500,000 sqm of colocation space across 160 data centers located in more than 20 countries and regions.

“Organizations today demand an ever-expanding global platform to reach their growing digital business objectives,” said Masaaki Moribayashi, Senior Executive Vice President, Services for NTT Ltd. “That’s why we continue to expand our portfolio of the best data centers in new and existing markets that complement our global geographic footprint.”


While meeting the growing demand from the market, NTT has also committed to following sustainable best practices where possible while growing its global data center platform.

“All our new data centers will be set up for clients to use renewable energy if they choose, as NTT invests in a sustainable future for our planet,” said Moribayashi. “Our data centers are strategically located to support interconnected ecosystems around the world’s most important business and government hubs and will include the latest data center technology for security, reliability and energy efficiency.”

NTT Ltd.’s Global Data Centers division will soon launch new data center capability in India, the UK, Japan, USA, Germany, Malaysia and Indonesia. When fully complete, these data centers will provide over 400 megawatts (MW) of IT load across these markets.

  • Mumbai, India – NTT Ltd. will go live with its new Mumbai 7 Data Center by Q3 2020 in its Chandivali campus. The Mumbai 7 Data Center will offer 25 MW of IT load. The Mumbai 7 Data Center will be the third data center in the Chandivali campus, totaling 61 MW of IT load and is well connected by fiber from all four sides. Also, this data center is a quick 15-minute drive from Chhatrapati Shivaji International Airport of Mumbai.
  • London, UK – NTT Ltd.’s new London 1 Data Center is scheduled to open during Q3 2020. The London 1 Data Center is capable of 64 MW at full buildout, with 8 MW available at the facility’s opening. This facility will interconnect with NTT Ltd.’s five existing data centers around London to deliver over 100MW of IT load when fully completed. The London 1 Data Center is in Dagenham, east London, close to London’s Docklands, which is the UK’s Internet hub and backbone for global connectivity, which facilitates the majority of the London Internet Exchanges (LINX’s).
  • Tokyo, Japan – For NTT Ltd.’s data center coverage in Japan, NTT Communications will complete a new data center that will be operational in Q3 2020.
    Hillsboro, Oregon, USA – NTT Ltd. is pre-leasing space now at its first data center campus in Hillsboro, Oregon. In Q3 2020, the first 6 MW at the Hillsboro 1 Data Center is coming online as part of an existing building that is being repurposed to the highest-level data center. NTT Ltd.’s 47-acre Hillsboro campus will eventually hold five data centers totaling 144 MW and will be directly connected to the ultra-high count fiber ring which serves as a cross connect for several transpacific submarine cables that reduce latency between the U.S. and high-growth Asian markets.
  • Ashburn, Virginia, USA – In Ashburn, Virginia, the largest and most sought-after data center market in the world, NTT Ltd. is constructing its fifth data center. The two-story Ashburn 5 Data Center will offer 32 MW, with 8 MW ready in Q3 2020. This will bring NTT Ltd.’s total Ashburn footprint to 108 MW over its five buildings. Three of those buildings are on NTT Ltd.’s fenced, secure, 78-acre Ashburn campus, which has room for four more buildings.
  • Munich, Germany – NTT Ltd. has completed the shell of its second building within the Munich 2 Data Center campus. The new building is scheduled to go online in Q4 2020 and once completed the campus will provide 14 MW of IT load for clients. The Munich area is the economical and digital hub of Southern Germany. The Munich 2 Data Center also hosts a Technology Experience Lab and is part of the scalable network and connectivity ecosystem of NTT.
  • Cyberjaya, Malaysia – NTT Ltd. is constructing its fifth data center at its Cyberjaya campus, which is 30 km away from the center of Kuala Lumpur. The new Cyberjaya 5 Data Center with 5.6 MW of critical IT load will come online in Q4 2020 and is designed to meet the requirements of hyperscalers and high-end enterprises.
  • Chicago, Illinois, USA – NTT Ltd. is pre-leasing now for the new Chicago data center campus located on a 19-acre site. A pair of two-story 36 MW buildings will total 72 MW of scalable critical IT load at full buildout. The first building, the Chicago 1 Data Center, will bring 6 MW online in Q1 2021.
  • Jakarta, Indonesia – NTT Ltd.’s new campus in Bekasi, Indonesia is capable of 45 MW of critical IT load once fully developed. The new campus, to be known as the Indonesia Jakarta 3 Data Center, will be the largest data center in Indonesia and is expected to open in the first half of 2021.

NTT Ltd. also has plans in place for next year to develop new data centers in Johannesburg, Silicon Valley, Madrid, and Phoenix, as well as building additional capacity in Mumbai, London, Vienna, Zurich, Berlin and Frankfurt.

“We are pleased to leverage our deep construction expertise and the strength of our capital resources to extend our line of data center facilities – with more to come,” said Ryuichi Matsuo, Executive Vice President for NTT Ltd.’s Global Data Centers division. “By increasing our global footprint during this pandemic, we can support our clients as their demand increases for reliable, robust cloud services, cloud communications, digital entertainment and new technology such as artificial intelligence.”

NTT Ltd. data center clients have access to full-stack technology solutions from data center, network, voice and video infrastructure and managed services. NTT Ltd. has vast expertise in building technologically advanced data centers with low total cost of ownership and high redundancy. NTT Ltd.’s global data center platform enables end-to-end solutions for clients to balance their critical IT load across most major global locations.

About the Global Data Centers division of NTT Ltd.
Global Data Centers is a division of NTT Ltd. and incorporates DPA, e-shelter, Gyron, Netmagic, NTT Indonesia Nexcenter, RagingWire and other NTT Communications group data center divisions. Our combined global platform is one of the largest in the world, with over 160 data centers spanning more than 20 countries and regions including North America, APAC, EMEA and India. As a neutral operator, we offer access to multiple cloud providers, a large variety of Internet Exchanges and telecommunication network providers including our own IPv6 compliant, tier 1 global IP network. Our clients include hyperscalers and global enterprises across all industries, including the financial, media, gaming, healthcare, manufacturing and retail industries and public sector.

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AMSTERDAM – Leaseweb Global, a leading hosting and cloud services provider, today announced the launch of Leaseweb Cloud Connect. A hybrid cloud solution, Leaseweb Cloud Connect enables customers to seamlessly connect their Leaseweb-hosted infrastructure to their public cloud or hyperscaler environment— and to allow sharing of data and applications between them. In partnership with Megaport, a leading Network as a Service provider, Leaseweb Cloud Connect will initially provide connectivity to AWS, with plans already in place to add other leading hyperscalers throughout the rest of the year.

Leaseweb Cloud Connect is designed for businesses that require the flexibility to move workloads between hyperscalers and Leaseweb’s infrastructure in line with changing demands and budgets. Customers will be able to select different connectivity speeds between 100Mbps and 10Gbps, depending on individual project and budget requirements. The new offering provides an elegant, tailored and cost-effective solution to address the lack of customization that many businesses experience when they decide to scale their infrastructure, services, applications, and data within a public cloud environment.


“Leaseweb Cloud Connect provides businesses with an efficient way to build secure networks that interconnect Cloud infrastructures across Leaseweb and public clouds,” said Nikolaos Kolestsas, Product Manager, Leaseweb Global. “The new offering delivers a hybrid cloud solution that allows businesses to use a public cloud for development, PaaS functions, one-off workloads, and big data platforms, all while leveraging Leaseweb for business-critical applications and associated data or specific production environments. Megaport’s Software Defined Network provides the scalable, secure connectivity to cloud onramps to ensure peak performance. This approach minimizes infrastructure costs and increases the speed at which organizations can bring new products and services to market.”

By using Leaseweb Cloud Connect to create a hybrid cloud environment that leverages Leaseweb’s secure and high-performance global network, coupled with a Megaport Connected solution, businesses can develop and distribute their services while gaining more control over their cloud-based infrastructure. Leaseweb Cloud Connect achieves this by providing a fast and secure connection to public cloud, which ensures dynamic and cost-effective allocation of resources across the hybrid cloud environment.

Part of Leaseweb’s Hybrid Connect Concept, Leaseweb Cloud Connect is a Megaport connected solution that is powered by Megaport’s Software Defined Networking technology and integrated with virtual public cloud interfaces and gateways. The Megaport Connected solution offers the broadest reach of cloud onramps across the globe with more than 170 cloud onramps. The collaboration provides Leaseweb with the opportunity to provide greater options to customers in connecting to public cloud infrastructure to design hybrid solutions that scale and perform.

“We are delighted that Leaseweb has chosen our Network as a Service platform to power its new solution,” said Eric Troyer, Chief Marketing Officer at Megaport. “Leaseweb Cloud Connect reinforces Leaseweb’s position within the hybrid cloud provider space and allows Leaseweb to provide an extended Cloud access service to their SMB and start-up customers. We value the partnership with Leaseweb and are excited to be able to support the company’s continued evolution as hybrid and multi-cloud demand continues to grow throughout Europe.”

Leaseweb Cloud Connect is suited to all organizations but offers particular benefits to start-ups and SMBs in the Adtech, Martech, Gaming, and SaaS sectors that are using public cloud providers but are seeking to scale their business—not their costs.

To learn more about Leaseweb Cloud Connect, please visit: https://www.leaseweb.com/network-services/cloud-connect

About Leaseweb
Leaseweb is a leading Infrastructure as a Service (IaaS) provider serving a worldwide portfolio of 18,000 customers ranging from SMBs to Enterprises. Services include Public Cloud, Private Cloud, Dedicated Servers, Colocation, Content Delivery Network, and Cyber Security Service s supported by exceptional customer service and technical support. With more than 80,000 servers under management, Leaseweb has provided infrastructure for mission-critical websites, Internet applications, email servers, security, and storage services since 1997. The company operates 20 data centers in locations across Europe, Asia, Australia, and North America, all of which are backed by a superior worldwide network with a total capacity of more than 10 Tbps. Leaseweb offers services through its various subsidiaries, which are Leaseweb Netherlands B.V. (“Leaseweb Netherlands”), Leaseweb USA, Inc. (“Leaseweb USA”), Leaseweb Asia Pacific PTE. LTD (“Leaseweb Asia”), Leaseweb CDN B.V. (“Leaseweb CDN”), Leaseweb Deutschland GmbH (“Leaseweb Germany”), Leaseweb Australia Ltd. (“Leaseweb Australia”) and Leaseweb UK Ltd (“Leaseweb UK”).

About Megaport
Megaport is a global leading Network as a Service provider. Using Software Defined Networking (SDN), the Company’s global platform enables customers to rapidly connect their network to other services across the Megaport Network. Services can be directly controlled by customers via mobile devices, their computer, or our open API. Megaport connects more than 1,700 customers in over 600 enabled data centres globally. Megaport is an Alibaba Cloud Technology Partner, AWS Technology Partner, AWS Networking Competency Partner, Google Cloud Interconnect Partner, IBM Direct Link Cloud Exchange provider, Microsoft Azure Express Route Partner, Nutanix Direct Connect Partner, Oracle Cloud Partner, Salesforce Express Connect Partner, and SAP PartnerEdge Open Ecosystem Partner.

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